APS-2-79 HCl

Catalog No. A16175

APS-2-79 HCl，稳定KSR（Ras激酶抑制剂）失活状态并拮抗致癌性Ras信号（IC50值为120 nM，对抗KSR2的ATP-生物素探针标记）的小分子。

Technical details

Catalog Num	A16175
M. Wt	423.89
Formula	C23H21N3O3.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	2002381-31-7
Synonyms	KSR/Ras Inhibitor
SMILES	CC1=C(C=CC(=C1)OC2=CC=CC=C2)NC3=NC=NC4=CC(=C(C=C43)OC)OC.Cl

Biological Activity

APS-2-79 HCl，稳定KSR（Ras激酶抑制剂）失活状态并拮抗致癌性Ras信号（IC50值为120 nM，对抗KSR2的ATP-生物素探针标记）的小分子。

Targets

KSR2
120 nM

Solubility *

In vitro	DMSO	82 mg/mL (193.44 mM)
	Water	Insoluble
	Ethanol	27 mg/mL (63.69 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.59 mL	117.96 mL	235.91 mL
0.5 mM	4.72 mL	23.59 mL	47.18 mL
1 mM	2.36 mL	11.8 mL	23.59 mL
5 mM	0.47 mL	2.36 mL	4.72 mL

*The above data is based on the productmolecular weight 423.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.