EAI045

Catalog No. A16193

EAI045是一种有效的选择性EGFR抑制剂。EAI045靶向选定的耐药性EGFR突变体，但保留了野生型受体。

Technical details

Catalog Num	A16193
M. Wt	383.4
Formula	C19H14FN3O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1942114-09-1
Synonyms	EAI-045, EAI 045
SMILES	FC1=CC=C(C(C(N2CC(C=CC=C3)=C3C2=O)C(NC4=NC=CS4)=O)=C1)O

Biological Activity

EAI045是一种有效的选择性EGFR抑制剂。EAI045靶向选定的耐药性EGFR突变体，但保留了野生型受体。

Targets

EGFR mutants

Solubility *

In vitro	DMSO	75 mg/mL (195.61 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.08 mL	130.41 mL	260.82 mL
0.5 mM	5.22 mL	26.08 mL	52.16 mL
1 mM	2.61 mL	13.04 mL	26.08 mL
5 mM	0.52 mL	2.61 mL	5.22 mL

*The above data is based on the productmolecular weight 383.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.