Crizotinib hydrochloride

Catalog No. A16245

Crizotinib hydrochloride是c-Met激酶和NPM-ALK的抑制剂。
  • Brittany M. Duggan, .et al. Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia, Sci Rep, 2017, 7: 1578 PMID: 28484277
Catalog Num A16245
M. Wt 486.8
Formula C21H23Cl3FN5O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415560-69-8
Synonyms PF-02341066 hydrochloride, PF 02341066 hydrochloride
SMILES C[C@](OC(C=C(C(C=N1)=CN1C2CCNCC2)C=N3)=C3N)([H])C4=C(Cl)C=CC(F)=C4Cl.Cl
Crizotinib hydrochloride是c-Met激酶和NPM-ALK的抑制剂。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.54 mL 102.71 mL 205.42 mL
0.5 mM 4.11 mL 20.54 mL 41.08 mL
1 mM 2.05 mL 10.27 mL 20.54 mL
5 mM 0.41 mL 2.05 mL 4.11 mL

*The above data is based on the productmolecular weight 486.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.