LFM-A13

Catalog No. A16261

LFM-A13是有效且选择性的Btk抑制剂，IC50为17.2 uM；也抑制PLK3，IC50为7.2 uM。

Technical details

Catalog Num	A16261
M. Wt	360
Formula	C11H8Br2N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	244240-24-2
Synonyms	LFM A13
SMILES	C/C(O)=C(/C(O)=N/C1=C(Br)C=CC(Br)=C1)C#N

Biological Activity

LFM-A13是有效且选择性的Btk抑制剂，IC50为17.2 uM；也抑制PLK3，IC50为7.2 uM。

Targets

BTK
2.5 μM

Solubility *

In vitro	DMSO	Warmed: 67 mg/mL (186.11 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.78 mL	138.89 mL	277.78 mL
0.5 mM	5.56 mL	27.78 mL	55.56 mL
1 mM	2.78 mL	13.89 mL	27.78 mL
5 mM	0.56 mL	2.78 mL	5.56 mL

*The above data is based on the productmolecular weight 360. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.