Amitriptyline HCl

Catalog No. A16404

Amitriptyline HCl抑制5-羟色胺受体，去甲肾上腺素受体，5-HT4、5-HT2和sigma 1受体，IC50分别为3.45 nM，13.3 nM，7.31 nM，235 nM和287 nM。

Technical details

Catalog Num	A16404
M. Wt	313.86
Formula	C20H23N.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	549-18-8
Synonyms
SMILES	CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

Biological Activity

Amitriptyline HCl抑制5-羟色胺受体，去甲肾上腺素受体，5-HT4、5-HT2和sigma 1受体，IC50分别为3.45 nM，13.3 nM，7.31 nM，235 nM和287 nM。

Solubility *

In vitro	DMSO	56 mg/mL (178.42 mM)
	Water	13 mg/mL (41.42 mM)
	Ethanol	56 mg/mL (178.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.86 mL	159.31 mL	318.61 mL
0.5 mM	6.37 mL	31.86 mL	63.72 mL
1 mM	3.19 mL	15.93 mL	31.86 mL
5 mM	0.64 mL	3.19 mL	6.37 mL

*The above data is based on the productmolecular weight 313.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Amitriptyline HCl

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions