AZD0156

Catalog No. A16419

AZD0156是有效且选择性的ATM激酶抑制剂,具有潜在的化学/放射致敏和抗肿瘤活性。
  • Yi-Ru Pan, .et al. ATM Inhibitor Suppresses Gemcitabine-Resistant BTC Growth in a Polymerase θ Deficiency-Dependent Manner, Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492
Catalog Num A16419
M. Wt 461.56
Formula C26H31N5O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1821428-35-6
Synonyms AZD-0156, AZD 0156
SMILES O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
AZD0156是有效且选择性的ATM激酶抑制剂,具有潜在的化学/放射致敏和抗肿瘤活性。
In vitro DMSO Warmed: <1 mg/mL
Water Insoluble
Ethanol 2 mg/mL (4.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.33 mL 216.66 mL
0.5 mM 4.33 mL 21.67 mL 43.33 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.