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DNA Damage

产品 1 到 50 共 416个

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  1. Dye 937
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    Dye 937

    Catalog No. A15072
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    Dye 937，具有选定渗透性的取代不对称花青染料，可用于电泳凝胶中的DNA检测。 了解更多
  2. HOE 32020
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    HOE 32020

    Catalog No. A15103
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    HOE 32020是一种Hoechst染料，它是一种用于对DNA染色的蓝色荧光染料。 了解更多
  3. HOE 32021
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    HOE 32021

    Catalog No. A15104
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    HOE 32021是DNA的细胞染料。 了解更多
  4. HOE 33187
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    HOE 33187

    Catalog No. A15105
    HOE 33187是DNA的细胞染料。 了解更多
  5. HOE-S 785026
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    HOE-S 785026

    Catalog No. A15116
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    Cell dye for DNA
    HOE-S 785026是DNA的细胞染料。 了解更多
  6. Nuclear yellow
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    Nuclear yellow

    Catalog No. A15193
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    Nuclear yellow与DNA结合时，它的最大激发/发射波长约为335/495 nm。 了解更多
  7. ortho-iodoHoechst 33258
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    ortho-iodoHoechst 33258

    Catalog No. A15199
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    ortho-iodoHoechst 33258属于Hoechst染料的一种，Hoechst 33258是能用于DNA定量的细胞染料。 了解更多
  8. para-iodoHoechst 33258
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    para-iodoHoechst 33258

    Catalog No. A15206
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    para-iodoHoechst 33258是用于对DNA染色的蓝色荧光染料家族的一部分。Hoechst 33258是用于DNA定量的细胞染料。 了解更多
  9. Hoechst 33258 trihydrochloride
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    Hoechst 33258 trihydrochloride

    Catalog No. A15106
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    Hoechst 33258 trihydrochloride是用于DNA定量的细胞染料 了解更多
  10. Hoechst 33258 analog
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    Hoechst 33258 analog

    Catalog No. A15107
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    Hoechst 33258 analog是用于DNA定量的细胞染料。 了解更多
  11. Hoechst 33258 analog 2
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    Hoechst 33258 analog 2

    Catalog No. A15108
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    Hoechst 33258 analog 2 是用于DNA定量的细胞染料。 了解更多
  12. Hoechst 33258 analog 3
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    Hoechst 33258 analog 3

    Catalog No. A15109
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    Hoechst 33258 analog 3 是用于DNA定量的细胞染料。 了解更多
  13. Hoechst 33258 analog 5
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    Hoechst 33258 analog 5

    Catalog No. A15110
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    Hoechst 33258 analog 5 是Hoechst染料的类似物，它是用于对DNA染色的蓝色荧光染料家族的一部分。 了解更多
  14. Hoechst 33258 analog 6
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    Hoechst 33258 analog 6

    Catalog No. A15111
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    Hoechst 33258 analog 6 是Hoechst染色剂（Hoechst 33258）的一册，这是用于对DNA染色的蓝色荧光染料家族的一部分。 了解更多
  15. Hoechst 33342
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    Hoechst 33342

    Catalog No. A15112
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    Blue fluorescent dyes
    Hoechst 33342是DNA的细胞染料。 了解更多
  16. Hoechst 33342 analog
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    Hoechst 33342 analog

    Catalog No. A15113
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    Blue fluorescent dyes
    Hoechst 33342 analog 是Hoechst染色的类似物，是用于对DNA染色的蓝色荧光染料家族的一部分。 了解更多
  17. Hoechst 33342 analog 2
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    Hoechst 33342 analog 2

    Catalog No. A15114
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    Blue fluorescent dyes
    Hoechst 33342 analog 2 是Hoechst染色的底物，它是用于染色DNA的蓝色荧光染料家族的一部分。 了解更多
  18. Hoechst 34580
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    Hoechst 34580

    Catalog No. A15115
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    Blue fluorescent dyes
    Hoechst 34580是DNA的细胞染料。 了解更多
  19. meta-iodoHoechst 33258
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    meta-iodoHoechst 33258

    Catalog No. A15158
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    meta-iodoHoechst 33258是用于对DNA染色的蓝色荧光染料家族的一部分。 了解更多
  20. APY29
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    APY29

    Catalog No. A13828
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    IRE1α 抑制剂
    APY29抑制IRE1α自磷酸化（IC50 = 280 nM），并激活IRE1αRNase活性。 了解更多
  21. 4μ8C
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    4μ8C

    Catalog No. A13803
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    IRE1 Rnase 抑制剂
    4μ8C是一种有效的选择性IRE1 Rnase抑制剂，IC50为76 nM。 了解更多
  22. AK-7
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    AK-7

    Catalog No. A12904
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    SIRT2 抑制剂
    AK-7是SIRT2的细胞和脑渗透抑制剂（IC50 = 15.5 μM）。 了解更多
  23. Inauhzin
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    Inauhzin

    Catalog No. A12527
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    SIRT1 抑制剂
    Inauhzin是一种有效的SirT1/IMPDH2 的双重抑制剂，可通过抑制SIRT1活性有效地重新激活p53，促进人类癌细胞的p53依赖性凋亡，而不会引起明显的遗传毒性应激。 了解更多
  24. AGK2
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    AGK2

    Catalog No. A14225
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    SIRT2 抑制剂
    AGK2是一种有效的选择性SIRT2抑制剂，IC50为3.5μM。 了解更多
  25. AK-1
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    AK-1

    Catalog No. A14370
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    SIRT2 抑制剂
    AK-1比SIRT1和SIRT3选择性抑制SIRT2。 了解更多
  26. Sirtinol
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    Sirtinol

    Catalog No. A12226
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    sirtuin 抑制剂
    Sirtinol是Sirtinol NAD依赖组蛋白去乙酰化酶的细胞渗透性特异性抑制剂。在无细胞分析中，它是一种特异性SIRT1和SIRT2抑制剂，IC50分别为131 μM和38 μM。 了解更多
  27. OSS-128167
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    OSS-128167

    Catalog No. A17048
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    SIRT 6 抑制剂
    OSS-128167，也称为SIRT6-IN-1，是一种有效的选择性SIRT 6抑制剂，IC50值为89 μM。 了解更多
  28. Thiomyristoyl
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    Thiomyristoyl

    Catalog No. A17166
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    SIRT2 抑制剂
    Thiomyristoyl是一种有效的特异性SIRT2抑制剂，IC50为28 nM。 了解更多
  29. 3-TYP
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    3-TYP

    Catalog No. A17144
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    SIRT3 抑制剂
    3-TYP是SIRT3抑制剂。 了解更多
  30. MDL-800
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    • 最新产品

    MDL-800

    Catalog No. A17228
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    SIRT6 allosteric activator
    MDL-800 is a first-in-class cellularly active SIRT6 allosteric activator. 了解更多
  31. CAY10602
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    CAY10602

    Catalog No. A19395
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    SIRT1 activator
    CAY10602 is a SIRT1 activator. 了解更多
  32. SRT 1460
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    SRT 1460

    Catalog No. A19026
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    SIRT1 activator
    SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues. 了解更多
  33. UBCS039
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    UBCS039

    Catalog No. A18961
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    SIRT6 activator
    UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM. 了解更多
  34. SRT 2183
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    SRT 2183

    Catalog No. A12150
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    Sirtuin-1 (SIRT1) activator
    SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels. 了解更多
  35. Cambinol
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    Cambinol

    Catalog No. A12381
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    SIRT1 and SIRT2 inhibitor
    Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively. 了解更多
  36. Salermide
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    Salermide

    Catalog No. A12263
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    Sirt1/Sirt2 inhibitor
    Salermide is an inhibitor of Sirt1 and Sirt2; can cause strong cancer-specific apoptotic cell death. 了解更多
  37. PROTAC Sirt2 Degrader-1
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    PROTAC Sirt2 Degrader-1

    Catalog No. A20005
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    Sirt2 degrader
    PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. 了解更多
  38. SRT 1720 Hydrochloride
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    SRT 1720 Hydrochloride

    Catalog No. A21143
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    SIRT1 activator of
    SRT 1720 Hydrochloride is a selective activator of SIRT1 with an EC50 of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3. 了解更多
  39. SIRT-IN-2
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    SIRT-IN-2

    Catalog No. A20961
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    SIRT1/2/3 inhibitor
    SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 μM, respectively. 了解更多
  40. SIRT-IN-1
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    SIRT-IN-1

    Catalog No. A20962
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    SIRT1/2/3 inhibitor
    SIRT-IN-1 is a potent inhibitor of SIRT1/2/3, with IC50s of 15, 10, 33 μM, respectively. 了解更多
  41. Sirt2-IN-1
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    Sirt2-IN-1

    Catalog No. A19348
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    Sirt2 inhibitor
    Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM. 了解更多
  42. JFD00244
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    JFD00244

    Catalog No. A19517
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    SIRT2 inhibitor
    JFD00244 is a sirtuin 2 (SIRT2) inhibitor. Anti-tumor effect. 了解更多
  43. SIRT5 inhibitor 1
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    SIRT5 inhibitor 1

    Catalog No. A19841
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    SIRT5 inhibitor
    SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM. 了解更多
  44. SirReal1-O-propargyl
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    SirReal1-O-propargyl

    Catalog No. A20091
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    Sirt2 inhibitor
    SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. 了解更多
  45. Fisetin (Fustel)
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    Fisetin (Fustel)

    Catalog No. A10388
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    Fisetin (Fustel)是有效的Sirtuin活化化合物(STAC)，可以调节Sirtuin。 了解更多
  46. Tenovin-6
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    Tenovin-6

    Catalog No. A12305
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    p53 activator
    Tenovin-6是tenovin-1的类似物。Tenovin-6在体外抑制纯化的人SIRT1、SIRT2和SIRT3的蛋白脱乙酰酶活性，IC50值分别为21、10和67 uM。 了解更多
  47. EX 527 (Selisistat)
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    EX 527 (Selisistat)

    Catalog No. A10377
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    SIRT1 抑制剂
    EX 527 (Selisistat)是一种有效的选择性SIRT1 III类组蛋白脱乙酰基酶抑制剂，在无细胞分析中的IC50为38 nM。 了解更多
  48. SRT2104 (GSK2245840)
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    SRT2104 (GSK2245840)

    Catalog No. A14188
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    SIRT1 activator
    SRT2104 (GSK2245840)是一种选择性sirt1激活剂，参与能量稳态的调节。 了解更多
  49. SirReal2
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    SirReal2

    Catalog No. A15902
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    Selective SIRT2 抑制剂
    SirReal2是一种有效的、同型选择性Sirt2抑制剂，IC50为140 nM。 了解更多
  50. SRT 1720
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    SRT 1720

    Catalog No. A15247
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    SIRT1 Activator
    SRT 1720是人类SIRT1（EC1.5 = 0.16μM）相对于最接近的瑟土因同系物SIRT2和SIRT3（SIRT2：EC1.5 = 37 uM；SIRT3：EC1.5> 300 uM）的选择性激活剂。 了解更多

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  1. HDAC (102)
  2. PARP (49)
  3. DNA-PK (14)
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  6. ATM / ATR (21)
  7. DNA, RNA Synthesis (54)
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  9. DNA alkylator (8)
  10. Synthases / Synthetases (17)
  11. MTH1 (3)
  12. Sirtuins (30)
  13. IRE1 (2)
  14. DNA Stain (19)
作用机制
  1. Inhibitor (抑制剂) (305)
  2. Agonist (激动剂) (1)
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  4. Degrader (降解剂) (1)
  5. Substrate (底物) (2)
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  1. DNA-PK (1)
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  30. PDE5 (1)
  31. SIRT1 (6)
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  34. Sirtuin (1)
  35. Tankyrase-1 (5)
  36. Tankyrase-2 (8)
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