Histone Acetyltransferases

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  1. Histone Acetyltransferase Inhibitor II

    Catalog No. A12331
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    cell permeable p300 inhibitor
    Histone Acetyltransferase Inhibitor II is a potent and cell permeable p300 inhibitor, with an IC50 of 5 ?M; Histone Acetyltransferase Inhibitor II can be used in cancer research. 了解更多
  2. SGC-CBP30

    Catalog No. A13227
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    CBP/p300 bromodomain 抑制剂
    SGC-CBP30是一种有效且选择性的CREBBP(CBP)和EP300抑制剂,无细胞试验中IC50分别为21 nM和38 nM。它们是一般的转录共激活因子。 了解更多
  3. I-CBP112

    Catalog No. A13165
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    CBP/p300 bromodomain 抑制剂
    I-CBP112是一种高效且选择性的p300/CBP溴结构域抑制剂(对于CBP,IC50为?0.14-0.17 uM,对于p300为?0.625 uM)。 了解更多
  4. TPOP146

    Catalog No. A12655
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    CBP/P300 benzoxazepine bromodomain inhibitor
    TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4. 了解更多
  5. GNE-049

    Catalog No. A20206
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    CBP inhibitor
    GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. 了解更多
  6. EML 425

    Catalog No. A16180
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    CBP/p300 抑制剂
    EML 425是一种可逆且非竞争性的CBP/p300抑制剂,具有细胞渗透性(IC50值分别为1.1和2.9 uM)。 了解更多
  7. CPI-637

    Catalog No. A16470
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    CBP/EP300 bromodomain 抑制剂
    CPI-637是一种选择性的,具有细胞活性的苯并二氮杂酮CBP/EP300溴结构域抑制剂。 了解更多
  8. A-485

    Catalog No. A16830
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    p300/CBP 抑制剂
    A-485是p300/CBP的强效选择性HAT抑制剂,在p300 TR-FRET分析中的IC50为10 nM,在CBP TR-FRET分析中的IC50为3 nM,选择性是紧密相关的HAT的1000倍以上。 了解更多
  9. GNE-207

    Catalog No. A18844
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    CBP bromodomain inhibitor
    GNE-207 is a novel, potent, and orally bioavailable inhibitor of the bromodomain of CBP. GNE-207 has excellent CBP potency (CBP IC50?=?1?nM, MYC EC50?=?18?nM), and it exhibits a good pharmacokinetic profile. 了解更多
  10. Remodelin

    Catalog No. A21985
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    acetyl-transferase protein NAT10 inhibitor
    Remodelin is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. 了解更多
  11. P300/CBP-IN-3

    Catalog No. A18544
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    p300/CBP histone acetyltransferase inhibitor
    P300/CBP-IN-3, a p300/CBP histone acetyltransferase inhibitor. 了解更多
  12. WM-1119

    Catalog No. A16828
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    lysine acetyltransferase KAT6A 抑制剂
    WM-1119是赖氨酸乙酰基转移酶KAT6A的高效选择性抑制剂,IC50为0.25 uM。它对KAT6A的活性分别是对KAT5或KAT7的1100倍和250倍。 了解更多
  13. MG149

    Catalog No. A14267
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    KAT5 (Tip60) HAT 抑制剂
    MG149是一种有效的组蛋白乙酰转移酶抑制剂,对Tip60和MOF的IC50为74 uM和47 uM。 了解更多
  14. Remodelin Hydrobromide

    Catalog No. A14215
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    NAT10 抑制剂
    Remodelin Hydrobromide是一种有效的乙酰转移酶NAT10抑制剂。 了解更多
  15. Anacardic Acid

    Catalog No. A14226
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    KAT5 (Tip60), p300/PCAF 抑制剂
    Anacardic Acid是p300和p300/CBP相关因子组蛋白乙酰转移酶的有效抑制剂。 了解更多
  16. NU 9056

    Catalog No. A13378
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    KAT5 (Tip60) HAT 抑制剂
    NU9056是一种选择性KAT5(Tip60)HAT抑制剂。对于KAT5,p300,pCAF和GCN5,IC50值分别为<2、60、36和> 100μM。抑制前列腺癌细胞系和蛋白质块中的蛋白质乙酰化。 了解更多
  17. C646

    Catalog No. A12815
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    p300/CBP 抑制剂
    C646是选择性的p300/CREB结合蛋白(CBP)抑制剂(Ki = 400 nM)。 了解更多
  18. Garcinol

    Catalog No. A12814
    HAT 抑制剂
    藤黄酚是从印度藤黄中分离的聚异戊二烯基二苯甲酮衍生物。 在体外和体内,它都是有效的组蛋白乙酰转移酶(HATs)p300(IC50 = 7?M)和PCAF(IC50 = 5?M)抑制剂。 了解更多

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