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5-HT2B receptor 拮抗剂

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产品目录号: A11165


产品名 目录号 价格 数量
RS-127445 5mg A11165-5
¥ 400.00
RS-127445 10mg A11165-10
¥ 700.00
RS-127445 50mg A11165-50
¥ 2,000.00
RS-127445 100mg A11165-100
¥ 3,200.00



RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 RS-127445 发表的文献 (1)
  • Takeshi Takayanagi, .et al. Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide, Fujita Medical Journal, 2015, 1(1), 1-5, 2015

Chemical Information

目录号 A11165
Mechanism of action Antagonist
分子量 281.33
化学分子式 C17H16FN3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 199864-87-4
Synonyms RS127445, MT 500, RS127,445
SMILES code CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.Cl
化学名称 4-(4-fluoro-1-naphthyl)-6-isopropylpyrimidin-2-amine



RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors.

5-HT2B 5-HT2B


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.55 mL 177.73 mL 355.45mL
0.5 mM 7.11 mL 35.55 mL 71.09 mL
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL

*The above data is based on the productmolecular weight 281.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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