订阅到源订阅

使用 'ET-A' 作为标签的产品

Quick View
Ambrisentan (BSF 208075)

Catalog No. A11291
Quick View

添加到收藏
EndothelinA receptor 拮抗剂

Ambrisentan (BSF 208075)充当内皮素受体拮抗剂，对A型内皮素受体（ETA）具有选择性。了解更多

Product Citations (3)

Bulk Inquiry Free Sample
- Naoki Dohi, .et al. Quantitative real-time measurement of endothelin-1-induced contraction in single non-activated hepatic stellate cells, PLoS One, 2021, 16(8): e0255656 PMID: 34343209
- Tony Ngo, .et al. Orphan receptor ligand discovery by pickpocketing pharmacological neighbors, Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882
- Toshiaki Okamoto, .et al. Antifibrotic effects of ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model, World J Hepatol, 2016, Aug 8; 8(22): 933-941 PMID: 27574547
Quick View
Bosentan

Catalog No. A11091
Quick View

添加到收藏
ETAR/ETBR 抑制剂

Bosentan是内皮素-1（ET-A）和内皮素B（ET-B）受体的竞争性拮抗剂。了解更多

Bulk Inquiry Free Sample
Quick View
Macitentan

Catalog No. A11492
Quick View

添加到收藏
Endothelin receptor 拮抗剂

Macitentan是一种口服活性非肽双重ETA/ETB(内皮素) receptor双重拮抗剂，IC50为0.5 nM/391 nM。用于治疗特发性肺纤维化(IPF)和肺动脉高压(PAH)。了解更多

Bulk Inquiry
Quick View
Sitaxsentan sodium (TBC-11251)

Catalog No. A11564
Quick View

添加到收藏
ETA receptor 拮抗剂

Sitaxsentan sodium (TBC-11251)是一种选择性内皮素受体A拮抗剂，IC50和Ki分别为1.4 nM和0.43 nM。了解更多

Bulk Inquiry Free Sample
Quick View
Zibotentan (ZD4054)

Catalog No. A11006
Quick View

添加到收藏
ETA-receptor 拮抗剂

Zibotentan (ZD4054)是一种有效且特异性的ETA受体（内皮素A受体）拮抗剂（IC50 = 21 nM），对ETB没有抑制活性。了解更多

Product Citations (1)

Bulk Inquiry
- Tony Ngo, .et al. Orphan receptor ligand discovery by pickpocketing pharmacological neighbors, Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882

Adooq Bioscience

使用 'ET-A' 作为标签的产品

Ambrisentan (BSF 208075)

Bosentan

Macitentan

Sitaxsentan sodium (TBC-11251)

Zibotentan (ZD4054)

JOIN OUR REWARDS PROGRAM TODAY AND START EARNING POINTS RIGHT AWAY !

Total item