Talarozole

目录号: A21124

retinoic acid metabolism blocking agent

Talarozole

Talarozole Chemical Structure

CAS NO. 201410-53-9

Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.

库存: 现货

规格 价格 数量
2 mg
¥ 1,080.00
5 mg
¥ 2,160.00
10 mg
¥ 4,200.00
50 mg
¥ 12,360.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.49 mL 132.45 mL 264.89 mL
0.5 mM 5.3 mL 26.49 mL 52.98 mL
1 mM 2.65 mL 13.24 mL 26.49 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21124
M. Wt 377.51
Formula C21H23N5S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 201410-53-9
Synonyms R115866, R 115866, R-115866
SMILES CCC(CC)C(C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4

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