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TIC10

Akt 抑制剂?€?

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产品目录号: A15903

库存状态:中国现货中国现货

产品名 目录号 价格 数量
TIC10 10mg A15903-10
¥ 800.00
TIC10 25mg A15903-25
¥ 1,800.00
TIC10 50mg A15903-50
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.

TIC10

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Chemical Information

目录号 A15903
Mechanism of action Inhibitor
分子量 386.49
化学分子式 C24H26N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1616632-77-9
Synonyms ONC-201
SMILES code CC1=CC=CC=C1CN(C2=NCCN32)C(C(C4)=C3CCN4CC5=CC=CC=C5)=O
化学名称 2,4,6,7,8,9-hexahydro-4-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one

生物活性

Description
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
Targets
Akt ERK

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.87 mL 129.37 mL 258.74mL
0.5 mM 5.17 mL 25.87 mL 51.75 mL
1 mM 2.59 mL 12.94 mL 25.87 mL
5 mM 0.52 mL 2.59 mL 5.17 mL

*The above data is based on the productmolecular weight 386.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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