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TRV130 HCl (Oliceridine)

促销

??- opioid receptor 激动剂

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产品目录号: A15444

库存状态:中国现货中国现货

产品名 目录号 价格 数量
TRV130 HCl 5mg A15444-5
¥ 1,500.00
TRV130 HCl 10mg A15444-10
¥ 2,500.00
TRV130 HCl 25mg A15444-25
¥ 5,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

TRV 130 HCl is a novel μ-opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling(pEC50=8.1), with potency and efficacy similar to morphine, but with far less beta-arrestin recruitment and receptor internalization.

TRV130 HCl (Oliceridine)

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Chemical Information

目录号 A15444
Mechanism of action Agonist
分子量 423.01
化学分子式 C22H31ClN2O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1401031-39-7
Synonyms TRV-130, TRV 130
SMILES code COC1=C(SC=C1)CNCCC2(CCOC3(C2)CCCC3)C4=CC=CC=N4.Cl
化学名称 N-[(3-methoxythiophen-2-yl)methyl]-2-[(9R)-9-pyridin-2-yl-6-oxaspiro[4.5]decan-9-yl]ethanamine;hydrochloride

生物活性

Description
TRV 130 HCl is a novel μ-opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling(pEC50=8.1), with potency and efficacy similar to morphine, but with far less beta-arrestin recruitment and receptor internalization.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.64 mL 118.2 mL 236.4mL
0.5 mM 4.73 mL 23.64 mL 47.28 mL
1 mM 2.36 mL 11.82 mL 23.64 mL
5 mM 0.47 mL 2.36 mL 4.73 mL

*The above data is based on the productmolecular weight 423.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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