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ZM 306416 hydrochloride


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产品目录号: A11955


产品名 目录号 价格 数量
ZM 306416 hydrochloride 10mg A11955-10
¥ 900.00
ZM 306416 hydrochloride 25mg A11955-25
¥ 1,800.00
ZM 306416 hydrochloride 50mg A11955-50
¥ 3,000.00
ZM 306416 hydrochloride 100mg A11955-100
¥ 5,000.00
ZM 306416 hydrochloride 10mM * 1mL in DMSO A11955-10mM-D
¥ 920.00



ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.

ZM 306416 hydrochloride




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Chemical Information

目录号 A11955
Mechanism of action Inhibitor
分子量 370.21
化学分子式 C16H13N3O2FCl.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 690206-97-4
Synonyms ZM-306416
SMILES code COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
化学名称 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride


ZM 306416 is a VEGF receptor tyrosine kinase inhibitor that inhibits KDR (IC50 = 100 nM) and Flt (IC50 = 2 uM) tyrosine kinases.
VEGFR1 Src Abl
0.33 μM0.33 μM1.3 μM


Solubility (25°C)* In vitro DMSO 67 mg/mL (200.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.01 mL 135.06 mL 270.12mL
0.5 mM 5.4 mL 27.01 mL 54.02 mL
1 mM 2.7 mL 13.51 mL 27.01 mL
5 mM 0.54 mL 2.7 mL 5.4 mL

*The above data is based on the productmolecular weight 370.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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