Atazanavir sulfate (BMS-232632-05)

Catalog No. A10096

Atazanavir sulfate (BMS-232632-05)是蛋白酶抑制剂（PI）类的抗逆转录病毒药物。是一种高选择性的 HIV-1蛋白酶抑制剂。

Technical details

Catalog Num	A10096
M. Wt	802.9
Formula	C38H52N6O7.H2SO4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	229975-97-7
Synonyms	BMS-232632-05, CGP-73547, Reyataz, Zrivada
SMILES	CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC.OS(=O)(=O)O

Biological Activity

Atazanavir sulfate (BMS-232632-05)是蛋白酶抑制剂（PI）类的抗逆转录病毒药物。是一种高选择性的 HIV-1蛋白酶抑制剂。

Targets

HIV protease (Cell-free assay)
2.66 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	92 mg/mL (114.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.45 mL	62.27 mL	124.55 mL
0.5 mM	2.49 mL	12.45 mL	24.91 mL
1 mM	1.25 mL	6.23 mL	12.45 mL
5 mM	0.25 mL	1.25 mL	2.49 mL

*The above data is based on the productmolecular weight 802.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.