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¥ 0.00 Adooq Bioscience是您值得信赖的创新和高性能生命科学试剂供应商 Learn More
Our Products Are Cited in Thousands of Peer-Reviewed Publications. Explore the collection of citations for selected Adooq products
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KRAS G12C covalent inhibitor
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AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
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MDM2 degrader
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MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 has the potential to be a new class of anticancer agent.
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PDGFR 抑制剂
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AG1295 is a PDGF receptor specific inhibitor.
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pan-RAS inhibitor
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Ras-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts.
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ABHD16A inhibitor
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KC01 is a covalent inhibitor of ABHD16A.
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pan-caspase inhibitor
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MX1013 is a dipeptide pan-caspase inhibitor that inhibits caspase-1, caspase-3, and caspase-6, 7, 8, and 9.
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PUN30119, also known as Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications.
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CHK1 inhibitor
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CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor. CCT245737 showed CHK1 IC50 = 1.3 nM, CHK2 IC50 = 2440 nM, G2 check point abrogation IC50 = 30 nM. Mouse F (oral)=100%.
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GPCR19 antagonist
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SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.
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COX-2 抑制剂
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Firocoxib is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor class, currently approved for use in dogs and horses.
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