Calcitriol (Rocaltrol)

Catalog No. A10173

Calcitriol (Rocaltrol)作为vitamin D的激素活性形式，是一种非选择性vitamin D receptor的激活剂，对vitamin D receptor的结合亲和力(IC50=0.4 nM)。

Technical details

Catalog Num	A10173
M. Wt	416.6
Formula	C27H44O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	32222-06-3
Synonyms	Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol, 1,25-dihydroxycholecalciferol, 1,25-dihydroxyvitamin D3
SMILES	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C

Biological Activity

Calcitriol (Rocaltrol)作为vitamin D的激素活性形式，是一种非选择性vitamin D receptor的激活剂，对vitamin D receptor的结合亲和力(IC50=0.4 nM)。

Targets

vitamin D receptor (Cell-free assay)

Solubility *

In vitro	DMSO	79 mg/mL (189.61 mM)
	Water	Insoluble
	Ethanol	79 mg/mL (189.61 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24 mL	120.02 mL	240.04 mL
0.5 mM	4.8 mL	24 mL	48.01 mL
1 mM	2.4 mL	12 mL	24 mL
5 mM	0.48 mL	2.4 mL	4.8 mL

*The above data is based on the productmolecular weight 416.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.