Carbamazepine

Catalog No. A10179

Carbamazepine是一种抗惊厥和稳定情绪的药物，主要用于治疗癫痫和双相情感障碍以及三叉神经痛。

Product Citations

Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Technical details

Catalog Num	A10179
M. Wt	236.27
Formula	C15H12N2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	298-46-4
Synonyms	CBZ
SMILES	C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N

Biological Activity

Carbamazepine是一种抗惊厥和稳定情绪的药物，主要用于治疗癫痫和双相情感障碍以及三叉神经痛。

Targets

Sodium channel
131 μM

Solubility *

In vitro (25°C)	DMSO	45 mg/mL (190.46 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (71.95 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	42.32 mL	211.62 mL	423.24 mL
0.5 mM	8.46 mL	42.32 mL	84.65 mL
1 mM	4.23 mL	21.16 mL	42.32 mL
5 mM	0.85 mL	4.23 mL	8.46 mL

*The above data is based on the productmolecular weight 236.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.