Etoposide (VP-16)
Catalog No. A10373
Etoposide (VP-16)是通过抑制topoisomerase II活性而抑制DNA合成。
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Catalog Num | A10373 |
---|---|
M. Wt | 588.6 |
Formula | C29H32O13 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 33419-42-0 |
Synonyms | VP16, Vepesid, etoposide phosphate |
SMILES | C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O |
Etoposide (VP-16)是通过抑制topoisomerase II活性而抑制DNA合成。
Targets
Topo II (Cell-free assay) | ||||
In vitro (25°C) | DMSO | 99 mg/mL (168.2 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+40% PEG 300+5% Tween 80+ddH2O | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.99 mL | 84.95 mL | 169.89 mL |
0.5 mM | 3.4 mL | 16.99 mL | 33.98 mL |
1 mM | 1.7 mL | 8.49 mL | 16.99 mL |
5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
*The above data is based on the productmolecular weight 588.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.