Metformin HCl

Catalog No. A10573

Metformin HCl降低肝细胞中高血糖症，主要通过抑制肝糖原的产生（肝脏糖异生作用)发挥作用。

Product Citations

Matthew A Schaller, .et al. Ex vivo SARS-CoV-2 infection of human lung reveals heterogeneous host defense and therapeutic responses, JCI Insight, 2021, Sep 22;6(18):e148003 PMID: 34357881
Matthew A. Schaller, .et al. In vitro infection of human lung tissue with SARS-CoV-2: Heterogeneity in host defense and therapeutic response, bioRxiv, 2021, January 21

Technical details

Catalog Num	A10573
M. Wt	165.6
Formula	C4H12ClN5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1115-70-4
Synonyms	Glucophage, Riomet, Diabex
SMILES	CN(C)C(=N)N=C(N)N.Cl

Biological Activity

Metformin HCl降低肝细胞中高血糖症，主要通过抑制肝糖原的产生（肝脏糖异生作用)发挥作用。

Targets

AMPK (Hepatocytes)

Solubility *

In vitro	DMSO	Insoluble
	Water	Warmed: 30 mg/mL (181.14 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	60.39 mL	301.93 mL	603.86 mL
0.5 mM	12.08 mL	60.39 mL	120.77 mL
1 mM	6.04 mL	30.19 mL	60.39 mL
5 mM	1.21 mL	6.04 mL	12.08 mL

*The above data is based on the productmolecular weight 165.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.