Ramipril

Catalog No. A10778

Ramipril是一种血管紧张素转化酶（ACE）抑制剂，IC50为5 nM。

Technical details

Catalog Num	A10778
M. Wt	416.51
Formula	C23H32N2O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	87333-19-5
Synonyms	Tritace, Altace
SMILES	CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O

Biological Activity

Ramipril是一种血管紧张素转化酶（ACE）抑制剂，IC50为5 nM。

Targets

ACE
5 nM

Solubility *

In vitro (25°C)	DMSO	76 mg/mL (182.46 mM)
	Water	Insoluble
	Ethanol	76 mg/mL (182.46 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.01 mL	120.05 mL	240.09 mL
0.5 mM	4.8 mL	24.01 mL	48.02 mL
1 mM	2.4 mL	12 mL	24.01 mL
5 mM	0.48 mL	2.4 mL	4.8 mL

*The above data is based on the productmolecular weight 416.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.