Sophocarpine

Catalog No. A10857

Sophocarpine是人类ether-à-go-go相关基因(HERG)抑制剂，IC(50)为0.2 mM。可以逆转异丙肾上腺素引起的心律失常并抑制I（Na），I（CaL）和I（Kr）电流。槐角果碱的电生理作用类似于胺碘酮，可能被认为是预期的抗心律失常药。

Technical details

Catalog Num	A10857
M. Wt	246.4
Formula	C15H22N2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	6483-15-4
Synonyms
SMILES	C1C[C@H]2CN3[C@H](CC=CC3=O)[C@@H]4[C@H]2N(C1)CCC4

Biological Activity

Targets

Solubility *

In vitro	DMSO	47 mg/mL (190.78 mM)
	Water	6 mg/mL (24.35 mM)
	Ethanol	47 mg/mL (190.78 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.58 mL	202.92 mL	405.84 mL
0.5 mM	8.12 mL	40.58 mL	81.17 mL
1 mM	4.06 mL	20.29 mL	40.58 mL
5 mM	0.81 mL	4.06 mL	8.12 mL

*The above data is based on the productmolecular weight 246.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.