Tamoxifen Citrate

Catalog No. A10885

Tamoxifen Citrate是哺乳动物甾醇异构酶的选择性和有效抑制剂。

Product Citations

Renu Sudhakar, .et al. Bazedoxifene, a Postmenopausal Drug, Acts as an Antimalarial and Inhibits Hemozoin Formation, Microbiol Spectr, 2022, Jun 29;10(3) PMID: 35616371
Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Technical details

Catalog Num	A10885
M. Wt	563.6
Formula	C26H29NO.C6H8O7
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	54965-24-1
Synonyms	Istubal
SMILES	CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Biological Activity

Tamoxifen Citrate是哺乳动物甾醇异构酶的选择性和有效抑制剂。

Targets

ER (Cell-free assay)

Solubility *

In vitro (25°C)	DMSO	95 mg/mL (168.54 mM)
	Water	Insoluble
	Ethanol	95 mg/mL
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.74 mL	88.72 mL	177.43 mL
0.5 mM	3.55 mL	17.74 mL	35.49 mL
1 mM	1.77 mL	8.87 mL	17.74 mL
5 mM	0.35 mL	1.77 mL	3.55 mL

*The above data is based on the productmolecular weight 563.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.