Zoledronic Acid

Catalog No. A11010

Zoledronic acid, 破骨细胞抑制剂，通过抑制甲羟戊酸途径诱导破骨细胞凋亡。

Technical details

Catalog Num	A11010
M. Wt	272.1
Formula	C5H10N2O7P2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	118072-93-8
Synonyms	Zometa, Zomera, Aclasta and Reclast
SMILES	C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O

Biological Activity

Zoledronic acid, 破骨细胞抑制剂，通过抑制甲羟戊酸途径诱导破骨细胞凋亡。

Targets

Rho (Cell-free assay)

Solubility *

In vitro	DMSO	<1 mg/mL
	Water	Insoluble
	Ethanol	0.1M NaOH (aq): 36 mg/mL (132.31 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	36.75 mL	183.76 mL	367.51 mL
0.5 mM	7.35 mL	36.75 mL	73.5 mL
1 mM	3.68 mL	18.38 mL	36.75 mL
5 mM	0.74 mL	3.68 mL	7.35 mL

*The above data is based on the productmolecular weight 272.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.