JTT-705 (Dalcetrapib)

Catalog No. A11213

JTT-705 (Dalcetrapib)是一种CETP抑制剂，抑制CETP是增加HDL-胆固醇并可能减少动脉粥样硬化的目标。

Technical details

Catalog Num	A11213
M. Wt	389.6
Formula	C23H35NO2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	211513-37-0
Synonyms	JTT705
SMILES	CCC(CC)CC1(CCCCC1)C(=O)NC2=CC=CC=C2SC(=O)C(C)C

Biological Activity

JTT-705 (Dalcetrapib)是一种CETP抑制剂，抑制CETP是增加HDL-胆固醇并可能减少动脉粥样硬化的目标。

Targets

rhCETP
0.2 μM

Solubility *

In vitro (25°C)	DMSO	66 mg/mL (169.41 mM)
	Water	Insoluble
	Ethanol	66 mg/mL (169.41 mM)
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.67 mL	128.34 mL	256.67 mL
0.5 mM	5.13 mL	25.67 mL	51.33 mL
1 mM	2.57 mL	12.83 mL	25.67 mL
5 mM	0.51 mL	2.57 mL	5.13 mL

*The above data is based on the productmolecular weight 389.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.