GW842166X

Catalog No. A11253

GW842166X是一种选择性的非大麻类CB2受体激动剂，EC50为63 nM，对CB1受体没有显著的活性。

Technical details

Catalog Num	A11253
M. Wt	449.25
Formula	C18H17Cl2F3N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	666260-75-9, 956013-38-0
Synonyms
SMILES	C1COCCC1CNC(=O)C2=CN=C(N=C2C(F)(F)F)NC3=C(C=C(C=C3)Cl)Cl

Biological Activity

GW842166X是一种选择性的非大麻类CB2受体激动剂，EC50为63 nM，对CB1受体没有显著的活性。

Targets

CB2
63 nM(EC50)

Solubility *

In vitro (25°C)	DMSO	18 mg/mL (40.06 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.26 mL	111.3 mL	222.59 mL
0.5 mM	4.45 mL	22.26 mL	44.52 mL
1 mM	2.23 mL	11.13 mL	22.26 mL
5 mM	0.45 mL	2.23 mL	4.45 mL

*The above data is based on the productmolecular weight 449.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.