Bepotastine Besilate

Catalog No. A11340

Bepotastine Besilate是组胺H1受体激动剂。

Product Citations

Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Technical details

Catalog Num	A11340
M. Wt	547.06
Formula	C27H31ClN2O6S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	190786-44-8
Synonyms
SMILES	C1CN(CCC1O[C@@H](C2=CC=C(C=C2)Cl)C3=CC=CC=N3)CCCC(=O)O.C1=CC=C(C=C1)S(=O)(=O)O

Biological Activity

Bepotastine Besilate是组胺H1受体激动剂。

Targets

Histamine H1 receptor
5.7(pIC50)

Solubility *

In vitro	DMSO	100 mg/mL (182.79 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.28 mL	91.4 mL	182.8 mL
0.5 mM	3.66 mL	18.28 mL	36.56 mL
1 mM	1.83 mL	9.14 mL	18.28 mL
5 mM	0.37 mL	1.83 mL	3.66 mL

*The above data is based on the productmolecular weight 547.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.