GW 5074

Catalog No. A11436

GW 5074是一种强效、选择性和细胞渗透性的c-Raf1激酶抑制剂。

Technical details

Catalog Num	A11436
M. Wt	520.94
Formula	C15H8Br2INO2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	220904-83-6
Synonyms	GW5074
SMILES	C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2

Biological Activity

GW 5074是一种强效、选择性和细胞渗透性的c-Raf1激酶抑制剂。

Targets

C-Raf
9 nM

Solubility *

In vitro (25°C)	DMSO	101 mg/mL (193.87 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.2 mL	95.98 mL	191.96 mL
0.5 mM	3.84 mL	19.2 mL	38.39 mL
1 mM	1.92 mL	9.6 mL	19.2 mL
5 mM	0.38 mL	1.92 mL	3.84 mL

*The above data is based on the productmolecular weight 520.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.