Laropiprant (MK0524)

Catalog No. A11483

Laropiprant (MK0524)与烟酸合用可降低血液胆固醇。是一种有效的,选择性的 DP receptor 拮抗剂,Ki 值为 0.57 nM,对 TP 受体的 Ki 值为 2.95 nM。
Catalog Num A11483
M. Wt 435.9
Formula C21H19ClFNO4S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 571170-77-9
Synonyms Cardaptive, MK 0524, MK-0524
SMILES CS(=O)(=O)C1=C2C(=CC(=C1)F)C3=C(N2CC4=CC=C(C=C4)Cl)[C@H](CC3)CC(=O)O
Laropiprant (MK0524)与烟酸合用可降低血液胆固醇。是一种有效的,选择性的 DP receptor 拮抗剂,Ki 值为 0.57 nM,对 TP 受体的 Ki 值为 2.95 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.94 mL 114.71 mL 229.41 mL
0.5 mM 4.59 mL 22.94 mL 45.88 mL
1 mM 2.29 mL 11.47 mL 22.94 mL
5 mM 0.46 mL 2.29 mL 4.59 mL

*The above data is based on the productmolecular weight 435.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.