Telithromycin (Ketek)
Catalog No. A11664
Telithromycin (Ketek)是一种酮内酯抗生素。它用于治疗轻度至中度的社区获得性肺炎。Telithromycin通过干扰细菌的蛋白质合成来防止细菌生长。Telithromycin与细菌核糖体的50S亚基结合，并阻止多肽链的生长。
- Hannah Cetuk, .et al. Partitioning of Seven Different Classes of Antibiotics into LPS Monolayers Supports Three Different Permeation Mechanisms through the Outer Bacterial Membrane, Langmuir, 2021, Feb 2;37(4):1372-1385 PMID: 33449700
| Catalog Num | A11664 |
|---|---|
| M. Wt | 812 |
| Formula | C43H65N5O10 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 191114-48-4 |
| Synonyms | |
| SMILES | CC[C@H]1[C@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@H](C(=O)O1)C)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=C4)C5=CN=CC=C5)C |
Telithromycin (Ketek)是一种酮内酯抗生素。它用于治疗轻度至中度的社区获得性肺炎。Telithromycin通过干扰细菌的蛋白质合成来防止细菌生长。Telithromycin与细菌核糖体的50S亚基结合，并阻止多肽链的生长。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.32 mL | 61.58 mL | 123.15 mL |
| 0.5 mM | 2.46 mL | 12.32 mL | 24.63 mL |
| 1 mM | 1.23 mL | 6.16 mL | 12.32 mL |
| 5 mM | 0.25 mL | 1.23 mL | 2.46 mL |
*The above data is based on the productmolecular weight 812. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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