Meclizine 2HCl
Catalog No. A11700
Meclizine是人类的孕烷X受体（hPXR）激动剂。它具有抗胆碱能，中枢神经系统抑制作用和局部麻醉作用。其止吐和抗眩晕作用尚不完全清楚，但其主要的抗胆碱能特性是部分原因。
| Catalog Num | A11700 |
|---|---|
| M. Wt | 463.87 |
| Formula | C25H27Cl2N2.2HCl |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1104-22-9 |
| Synonyms | Meclozine |
| SMILES | CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl |
Meclizine是人类的孕烷X受体（hPXR）激动剂。它具有抗胆碱能，中枢神经系统抑制作用和局部麻醉作用。其止吐和抗眩晕作用尚不完全清楚，但其主要的抗胆碱能特性是部分原因。
| In vitro (25°C) | DMSO | Warmed: 4 mg/mL (8.62 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+95% Corn oil | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.56 mL | 107.79 mL | 215.58 mL |
| 0.5 mM | 4.31 mL | 21.56 mL | 43.12 mL |
| 1 mM | 2.16 mL | 10.78 mL | 21.56 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.31 mL |
*The above data is based on the productmolecular weight 463.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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