Argatroban

Catalog No. A11774

Argatroban是一种抗凝剂，是一种小分子直接凝血酶抑制剂，Ki值范围为5 nM-39 nM。

Technical details

Catalog Num	A11774
M. Wt	508.6
Formula	C23H36N6O5S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	74863-84-6
Synonyms
SMILES	C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C

Biological Activity

Argatroban是一种抗凝剂，是一种小分子直接凝血酶抑制剂，Ki值范围为5 nM-39 nM。

Targets

Thrombin
5-39 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	8 mg/mL (15.72 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (9.83 mM)
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.66 mL	98.31 mL	196.62 mL
0.5 mM	3.93 mL	19.66 mL	39.32 mL
1 mM	1.97 mL	9.83 mL	19.66 mL
5 mM	0.39 mL	1.97 mL	3.93 mL

*The above data is based on the productmolecular weight 508.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.