Bufalin

Catalog No. A12022

Bufalin是蟾酥中的有效活性成分，为有效的 Na+/K+-ATPase 抑制剂，可与其基 α1, α2 和 α3 结合，Kd 值分别为 42.5，45 和 40 nM。具有抗肿瘤活性。

Technical details

Catalog Num	A12022
M. Wt	386.5
Formula	C24H34O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	465-21-4
Synonyms
SMILES	C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4C5=COC(=O)C=C5)O)C)O

Biological Activity

Bufalin是蟾酥中的有效活性成分，为有效的 Na+/K+-ATPase 抑制剂，可与其基 α1, α2 和 α3 结合，Kd 值分别为 42.5，45 和 40 nM。具有抗肿瘤活性。

Solubility *

In vitro	DMSO	72 mg/mL (186.28 mM)
	Water	<1 mg/mL
	Ethanol	37 mg/mL (95.72 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.87 mL	129.37 mL	258.73 mL
0.5 mM	5.17 mL	25.87 mL	51.75 mL
1 mM	2.59 mL	12.94 mL	25.87 mL
5 mM	0.52 mL	2.59 mL	5.17 mL

*The above data is based on the productmolecular weight 386.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Bufalin

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions