PF 4981517
Catalog No. A12544
PF 4981517是一种有效且选择性的CYP3A4抑制剂(CYP3A4,CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM)。
Catalog Num | A12544 |
---|---|
M. Wt | 456.59 |
Formula | C26H32N8 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1390637-82-7 |
Synonyms | PF4981517, PF-4981517 |
SMILES | CC1=CC=C(C=C1)C2=C(C=NN2C)C3=NN(C4=C3C(=NC=N4)N5CC[C@@H](C5)N6CCCCC6)C |
PF 4981517是一种有效且选择性的CYP3A4抑制剂(CYP3A4,CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM)。
Targets
CYP3A4 | ||||
30 nM |
In vitro | DMSO | 85 mg/mL (186.16 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.9 mL | 109.51 mL | 219.01 mL |
0.5 mM | 4.38 mL | 21.9 mL | 43.8 mL |
1 mM | 2.19 mL | 10.95 mL | 21.9 mL |
5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
*The above data is based on the productmolecular weight 456.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.