BMS-345541
Catalog No. A12559
BMS-345541是IKK-2和IKK-1催化亚基的高度选择性抑制剂,IC50为0.3 μM和4 μM。
Catalog Num | A12559 |
---|---|
M. Wt | 255.32 |
Formula | C14H17N5 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 445430-58-0 |
Synonyms | BMS345541, BMS 345541 |
SMILES | CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN |
BMS-345541是IKK-2和IKK-1催化亚基的高度选择性抑制剂,IC50为0.3 μM和4 μM。
Targets
IKK2 (Cell-free assay) | IKK1 (Cell-free assay) | |||
0.3 μM | 4 μM |
In vitro | DMSO | 8 mg/mL (31.32 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 39.17 mL | 195.83 mL | 391.67 mL |
0.5 mM | 7.83 mL | 39.17 mL | 78.33 mL |
1 mM | 3.92 mL | 19.58 mL | 39.17 mL |
5 mM | 0.78 mL | 3.92 mL | 7.83 mL |
*The above data is based on the productmolecular weight 255.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.