Ouabain

Catalog No. A12755

Ouabain是一种选择性的Na+，K+-ATPase抑制剂。

Product Citations

Paul Mark Medina, .et al. Revealing the anticancer potential of candidate drugs in vivo using Caenorhabditis elegans mutant strains, Transl Oncol, 2021, Jan;14(1):100940 PMID: 33221682

Technical details

Catalog Num	A12755
M. Wt	584.66
Formula	C29H44O12
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	630-60-4
Synonyms
SMILES	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O

Biological Activity

Ouabain是一种选择性的Na+，K+-ATPase抑制剂。

Targets

α3	α2
15 nM(Ki)	41 nM(Ki)

Solubility *

In vitro	DMSO	87 mg/mL (119.37 mM)
	Water	Insoluble
	Ethanol	87 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.1 mL	85.52 mL	171.04 mL
0.5 mM	3.42 mL	17.1 mL	34.21 mL
1 mM	1.71 mL	8.55 mL	17.1 mL
5 mM	0.34 mL	1.71 mL	3.42 mL

*The above data is based on the productmolecular weight 584.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.