AGI-5198 (IDH-C35)
Catalog No. A12902
AGI-5198 (IDH-C35)是一种非常有效的选择性IDH1突变抑制剂,具有潜在的抗癌活性。
Catalog Num | A12902 |
---|---|
M. Wt | 462.56 |
Formula | C27H31FN4O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1355326-35-0 |
Synonyms | AGI5198,AGI 5198, IDHC35 |
SMILES | CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C |
AGI-5198 (IDH-C35)是一种非常有效的选择性IDH1突变抑制剂,具有潜在的抗癌活性。
Targets
R132H-IDH1 | R132C-IDH1 | |||
70 nM | 0.16 μM |
In vitro (25°C) | DMSO | 22 mg/mL (47.56 mM) | |
Water | Insoluble | ||
Ethanol | 13 mg/mL (28.1 mM) | ||
In vivo | 0.5% methylcellulose+0.2% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.62 mL | 108.09 mL | 216.19 mL |
0.5 mM | 4.32 mL | 21.62 mL | 43.24 mL |
1 mM | 2.16 mL | 10.81 mL | 21.62 mL |
5 mM | 0.43 mL | 2.16 mL | 4.32 mL |
*The above data is based on the productmolecular weight 462.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.