Vidofludimus (4SC-101)

Catalog No. A12997

Vidofludimus是一种新型的口服活性强效DHODH抑制剂。对人DHODH的IC50为134 nM。

Technical details

Catalog Num	A12997
M. Wt	355.36
Formula	C20H18FNO4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	717824-30-1
Synonyms	4SC 101, 4SC101, 4SC-101, SC12267, SC-12267, SC 12267
SMILES	COC1=CC=CC(=C1)C2=CC(=C(C=C2)NC(=O)C3=C(CCC3)C(=O)O)F

Biological Activity

Vidofludimus是一种新型的口服活性强效DHODH抑制剂。对人DHODH的IC50为134 nM。

Targets

Human DHODH
134 nM

Solubility *

In vitro (25°C)	DMSO	Warmed: 96 mg/mL (270.14 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL (2.81 mM)
In vivo	Suspended in water	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.14 mL	140.7 mL	281.4 mL
0.5 mM	5.63 mL	28.14 mL	56.28 mL
1 mM	2.81 mL	14.07 mL	28.14 mL
5 mM	0.56 mL	2.81 mL	5.63 mL

*The above data is based on the productmolecular weight 355.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.