NMS-1286937
Catalog No. A13045
NMS-1286937是一种小分子Polo样激酶1(PLK1)抑制剂,具有潜在的抗肿瘤活性。
Catalog Num | A13045 |
---|---|
M. Wt | 532.52 |
Formula | C24H27F3N8O3 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1034616-18-6 |
Synonyms | NMS1286937, NMS-P937 |
SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO |
NMS-1286937是一种小分子Polo样激酶1(PLK1)抑制剂,具有潜在的抗肿瘤活性。
Targets
PLK1 | PLK2 | PLK3 | ||
2 nM | >10 μM | >10 μM |
In vitro | DMSO | Warmed: 38 mg/mL (71.36 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 9 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.78 mL | 93.89 mL | 187.79 mL |
0.5 mM | 3.76 mL | 18.78 mL | 37.56 mL |
1 mM | 1.88 mL | 9.39 mL | 18.78 mL |
5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
*The above data is based on the productmolecular weight 532.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.