alpha-Amyloid Precursor Protein Modulator
Catalog No. A13094
α-淀粉样前体蛋白调节剂是细胞可渗透的苯并内酰胺衍生的PKC激活剂（PKCα的Ki = 11.9 nM），即使在人类原纤维中为100 nM时，也能有效增强淀粉样前体蛋白（APP）的非淀粉样生成性α-加工。
| Catalog Num | A13094 |
|---|---|
| M. Wt | 501.5 |
| Formula | C27H30F3N3O3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 497259-23-1 |
| Synonyms | PKC Activator V |
| SMILES | CC(C)[C@H]1C(=O)N[C@@H](CC2=C(N1C)C=CC(=C2)NC(=O)/C=C/C=C/C3=CC=C(C=C3)C(F)(F)F)CO |
α-淀粉样前体蛋白调节剂是细胞可渗透的苯并内酰胺衍生的PKC激活剂（PKCα的Ki = 11.9 nM），即使在人类原纤维中为100 nM时，也能有效增强淀粉样前体蛋白（APP）的非淀粉样生成性α-加工。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.94 mL | 99.7 mL | 199.4 mL |
| 0.5 mM | 3.99 mL | 19.94 mL | 39.88 mL |
| 1 mM | 1.99 mL | 9.97 mL | 19.94 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
*The above data is based on the productmolecular weight 501.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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