AF-353

Catalog No. A13131

AF-353是一种新型、有效的P2X3/P2X2/3受体拮抗剂，可抑制人和大鼠的P2X3（pIC50 = 8.0）。

Technical details

Catalog Num	A13131
M. Wt	400.21
Formula	C14H17IN4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	865305-30-2
Synonyms	AF353, AF 353
SMILES	CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)N)I)OC

Biological Activity

AF-353是一种新型、有效的P2X3/P2X2/3受体拮抗剂，可抑制人和大鼠的P2X3（pIC50 = 8.0）。

Solubility *

In vitro	DMSO	86 mg/mL (214.88 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.49 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.99 mL	124.93 mL	249.87 mL
0.5 mM	5 mL	24.99 mL	49.97 mL
1 mM	2.5 mL	12.49 mL	24.99 mL
5 mM	0.5 mL	2.5 mL	5 mL

*The above data is based on the productmolecular weight 400.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

AF-353

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions