GS-9620

Catalog No. A13251

GS-9620是Toll样受体7的有效选择性口服活性小分子激动剂。

Product Citations

Yu-Geun Ji, .et al. Determination of motolimod concentration in rat plasma by liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study, J Pharm Biomed Anal, 2019, 12 November, 112987
Zhikuan Zhang, .et al. Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands, Cell Reports, 2018, 25(12): 3371-3381.e5 PMID: 30566863

Technical details

Catalog Num	A13251
M. Wt	410.51
Formula	C22H30N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1228585-88-3
Synonyms	GS9620, GS 9620
SMILES	CCCCOC1=NC2=C(C(=N1)N)NC(=O)CN2CC3=CC(=CC=C3)CN4CCCC4

Biological Activity

GS-9620是Toll样受体7的有效选择性口服活性小分子激动剂。

Targets

TLR7

Solubility *

In vitro	DMSO	1 mg/mL (2.43 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.36 mL	121.8 mL	243.6 mL
0.5 mM	4.87 mL	24.36 mL	48.72 mL
1 mM	2.44 mL	12.18 mL	24.36 mL
5 mM	0.49 mL	2.44 mL	4.87 mL

*The above data is based on the productmolecular weight 410.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.