Ponesimod

Catalog No. A13307

Ponesimod是一种口服活性，选择性鞘氨醇-1-磷酸受体1（S1P1）免疫调节剂，EC50为5.7 nM。

Technical details

Catalog Num	A13307
M. Wt	460.97
Formula	C23H25ClN2O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	854107-55-4
Synonyms	ACT-128800
SMILES	O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC

Biological Activity

Ponesimod是一种口服活性，选择性鞘氨醇-1-磷酸受体1（S1P1）免疫调节剂，EC50为5.7 nM。

Targets

S1P1 receptor
5.7 nM(EC50)

Solubility *

In vitro	DMSO	82 mg/mL (177.88 mM)
	Water	Insoluble
	Ethanol	82 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.69 mL	108.47 mL	216.93 mL
0.5 mM	4.34 mL	21.69 mL	43.39 mL
1 mM	2.17 mL	10.85 mL	21.69 mL
5 mM	0.43 mL	2.17 mL	4.34 mL

*The above data is based on the productmolecular weight 460.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.