TAK-700 Salt (Orteronel Salt)

Catalog No. A13515

TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸，肾上腺和前列腺肿瘤组织中表达的酶CYP17A。

Technical details

Catalog Num	A13515
M. Wt	532.54
Formula	C28H28N4O7
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	426219-53-6
Synonyms	TAK 700, TAK700
SMILES	CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)C3(CCN4C3=CN=C4)O.C1=CC=C(C=C1)NC(=O)[C@H]([C@@H](C(=O)O)O)O

Biological Activity

TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸，肾上腺和前列腺肿瘤组织中表达的酶CYP17A。

Solubility *

In vitro (25°C)	DMSO	57 mg/mL (185.46 mM)
	Water	Insoluble
	Ethanol	8 mg/mL
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.78 mL	93.89 mL	187.78 mL
0.5 mM	3.76 mL	18.78 mL	37.56 mL
1 mM	1.88 mL	9.39 mL	18.78 mL
5 mM	0.38 mL	1.88 mL	3.76 mL

*The above data is based on the productmolecular weight 532.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

TAK-700 Salt (Orteronel Salt)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions