(-)-Blebbistcitin

Catalog No. A13647

(-)-Blebbistcitin是有效且选择性的 myosin II 抑制剂，IC50 范围为0.5至5 μM。

Technical details

Catalog Num	A13647
M. Wt	292.33
Formula	C18H16N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	856925-71-8
Synonyms	(S)-Blebbistatin
SMILES	CC1=CC2=C(C=C1)N=C3[C@](C2=O)(CCN3C4=CC=CC=C4)O

Biological Activity

(-)-Blebbistcitin是有效且选择性的 myosin II 抑制剂，IC50 范围为0.5至5 μM。

Targets

non-muscle myosin II ATPases (Cell-free assay)
0.5 μM-5 μM

Solubility *

In vitro (25°C)	DMSO	55 mg/mL (188.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.21 mL	171.04 mL	342.08 mL
0.5 mM	6.84 mL	34.21 mL	68.42 mL
1 mM	3.42 mL	17.1 mL	34.21 mL
5 mM	0.68 mL	3.42 mL	6.84 mL

*The above data is based on the productmolecular weight 292.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.