Zearalenone
Catalog No. A13740
Zearalenone是通常由镰刀菌属物种产生的一种植物雌激素真菌毒素，被证明是一种细胞毒性化合物，但芦荟结合雌激素受体（ER）（ERβ和ERα的IC50值分别为166和240 nM），并被发现可以刺激转录。两种亚型的活性在1-10 nM之间。
- Muthulakshmi S, .et al. Mycotoxin zearalenone induced gonadal impairment and altered gene expression in the hypothalamic-pituitary-gonadal axis of adult female zebrafish (Danio rerio), J Appl Toxicol, 2018, Nov;38(11):1388-1397 PMID: 29923290
| Catalog Num | A13740 |
|---|---|
| M. Wt | 318.36 |
| Formula | C18H22O5 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 17924-92-4 |
| Synonyms | |
| SMILES | C[C@H]1CCCC(=O)CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O |
Zearalenone是通常由镰刀菌属物种产生的一种植物雌激素真菌毒素，被证明是一种细胞毒性化合物，但芦荟结合雌激素受体（ER）（ERβ和ERα的IC50值分别为166和240 nM），并被发现可以刺激转录。两种亚型的活性在1-10 nM之间。
| In vitro | DMSO | 56 mg/mL (175.9 mM) | |
| Water | Insoluble | ||
| Ethanol | 56 mg/mL (175.9 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.41 mL | 157.05 mL | 314.11 mL |
| 0.5 mM | 6.28 mL | 31.41 mL | 62.82 mL |
| 1 mM | 3.14 mL | 15.71 mL | 31.41 mL |
| 5 mM | 0.63 mL | 3.14 mL | 6.28 mL |
*The above data is based on the productmolecular weight 318.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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