PTC-209

Catalog No. A13826

PTC-209是一种新型的有效选择性BMI-1抑制剂，靶向BMI-1自我更新机制，IC50为?0.5μM。

Technical details

Catalog Num	A13826
M. Wt	495.19
Formula	C17H13Br2N5OS
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	315704-66-6
Synonyms	PTC209, PTC 209
SMILES	CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br

Biological Activity

PTC-209是一种新型的有效选择性BMI-1抑制剂，靶向BMI-1自我更新机制，IC50为?0.5μM。

Targets

BMI-1 (HEK293T cells)
0.5 μM

Solubility *

In vitro	DMSO	92 mg/mL (185.78 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.19 mL	100.97 mL	201.94 mL
0.5 mM	4.04 mL	20.19 mL	40.39 mL
1 mM	2.02 mL	10.1 mL	20.19 mL
5 mM	0.4 mL	2.02 mL	4.04 mL

*The above data is based on the productmolecular weight 495.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.