CGP 57380

Catalog No. A13883

CGP 57380是MAP激酶相互作用激酶1（Mnk1，MKNK1）（IC50 = 2.2 uM）的抑制剂。

Technical details

Catalog Num	A13883
M. Wt	244.23
Formula	C11H9FN6
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	522629-08-9
Synonyms	CGP57380, CGP-57380
SMILES	C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F

Biological Activity

CGP 57380是MAP激酶相互作用激酶1（Mnk1，MKNK1）（IC50 = 2.2 uM）的抑制剂。

Targets

MNK1
2.2 μM

Solubility *

In vitro (25°C)	DMSO	Warmed: 43 mg/mL (176.06 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.95 mL	204.73 mL	409.45 mL
0.5 mM	8.19 mL	40.95 mL	81.89 mL
1 mM	4.09 mL	20.47 mL	40.95 mL
5 mM	0.82 mL	4.09 mL	8.19 mL

*The above data is based on the productmolecular weight 244.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.