DDR1-IN-1

Catalog No. A13985

DDR1-IN-1是一种有效的选择性DDR1受体酪氨酸激酶抑制剂，IC50/EC50为105 nM/87 nM，对DDR2的效力低4倍（IC50 = 413 nM）。

Technical details

Catalog Num	A13985
M. Wt	552.59
Formula	C30H31F3N4O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1449685-96-4
Synonyms
SMILES	CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F

Biological Activity

DDR1-IN-1是一种有效的选择性DDR1受体酪氨酸激酶抑制剂，IC50/EC50为105 nM/87 nM，对DDR2的效力低4倍（IC50 = 413 nM）。

Targets

DDR1	DDR2
105 nM	413 nM

Solubility *

In vitro	DMSO	Warmed: 87 mg/mL (157.44 mM)
	Water	Insoluble
	Ethanol	Warmed: 3 mg/mL (5.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.1 mL	90.48 mL	180.97 mL
0.5 mM	3.62 mL	18.1 mL	36.19 mL
1 mM	1.81 mL	9.05 mL	18.1 mL
5 mM	0.36 mL	1.81 mL	3.62 mL

*The above data is based on the productmolecular weight 552.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.