UNC 2250

Catalog No. A14143

UNC2250是一种有效的选择性Mer激酶抑制剂。

Technical details

Catalog Num	A14143
M. Wt	440.58
Formula	C24H36N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1493694-70-4
Synonyms	UNC-2250,UNC2250
SMILES	CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C3=NC=C(C=C3)CN4CCOCC4

Biological Activity

UNC2250是一种有效的选择性Mer激酶抑制剂。

Targets

Mer	Tyro3	Axl
1.7 nM	100 nM	270 nM

Solubility *

In vitro (25°C)	DMSO	Warmed: 2 mg/mL (4.53 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	0.4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.7 mL	113.49 mL	226.97 mL
0.5 mM	4.54 mL	22.7 mL	45.39 mL
1 mM	2.27 mL	11.35 mL	22.7 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

*The above data is based on the productmolecular weight 440.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.